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About Us

Catalyzing Innovation Since 1988

Since 1988, BIO-CAT has been the enzyme industry leader. Today they are also the leading Bacillus experts. BIO-CAT’s driven purpose is to partner with brilliant people who want to improve human and animal nutrition, water, soil, and more through innovative applications of enzymes and microbials. Taking ideas from incubation through every stage of development to achieve their fullest potential, BIO-CAT and BIO-CAT Microbials offer a carefully curated portfolio of natural, non-engineered enzymes and microbials for custom Enzyme solutions and Probiotic product innovation.

BIO-CAT focuses on complete customer service, providing only the highest quality enzymes to formulators, manufacturers and consumers. BIO-CAT’s exclusive relationship with the two top-tier Japanese enzyme manufacturers ensures only the highest quality enzymes available to all U.S. supplement manufacturers. Their expanding portfolio of proteases and peptidases, for the efficient utilization and increasing consumption of protein, further differentiates BIO-CAT from the rest of the industry. Custom blending and formulating, just-in-time inventory management, regulatory support and a top tier quality control lab comprise BIO-CAT’s industry leading customer service.

BIO-CAT Microbials is proud of their continually expanding library of well-characterized Bacillus strains for Human Health, Animal Nutrition, and sustainable Crop Science. These strains are produced in a fully-integrated U.S. fermentation facility in Minnesota, and are available to strategic partners for discovery and product development projects.

The original BIO-CAT building, 1990

Your Partner From R&D to Manufacturing


Nimble operation allows extensive customization and fast lead times

Customer Service

With you through product selection, development, and follow-up

Regulatory Support

Guiding companies of all sizes through the regulatory process

In-House R&D

Deep pipeline, giving you the confidence of solid science

Best-in-Class Manufacturing

Vertically integrated U.S. manufacturing with great flexibility


Known for our long standing customer relationships based on trust


Continuing a Legacy

Edward Schuler and his son Chris Schuler founded BIO-CAT in Keswick, Virginia in 1988, along with their business partner Brian Huffman. They began as a wholesaler of enzymes and enzyme blends, with a commitment to exceptional customer service. They grew the company steadily over the ensuing years, building larger facilities and expanding their capabilities.

In 2004, we acquired Advanced Microbial Systems and changed the name to BIO-CAT Microbials. This new undertaking, based in Shakopee, Minnesota, enabled us to combine unique enzymes with bacillus fermentation products.

Today, BIO-CAT and BIO-CAT Microbials offer an extensive range of products, including natural enzymes and blends and non-GMO microbials. The company is home to more than 70 employees and an ever expanding collection of top quality equipment. We operate an FSSC 22000 certified facility in Virginia featuring state-of-the-art laboratories for scientific research, product development and on-site quality testing to better serve you, our customers.


Meet Our Team

We select leaders and team members who share our pioneering spirit, along with deep experience in business and bioscience. Many of our employees have been with us for decades, continuously innovating and staying current in the biotech industry. Their breadth and depth of expertise lets them collaborate to discover big picture solutions.

BIO-CAT’s employees share an owner mentality towards the company, which means they put ego aside to focus on shared team goals in the best interest of the customer.


Certifications that Matter to You

BIO-CAT can assure customers of our quality thanks to these certifications and memberships:

  • BIO-CAT, Virginia is FSSC 22000 certified and registered as a Food Facility with the FDA

  • BIO-CAT Microbials, Minnesota is SQF certified and registered as a Food Facility with the FDA

  • Certified Kosher by the Orthodox Union

  • Certified Halal by the Islamic Food and Nutrition Council of America

  • Non-GMO and vegan probiotic strains


Focused on Ownable Differentiation

Our researchers work tirelessly to make new discoveries and test opportunities within the enzymes and microbials industry. Their research is regularly accepted into peer reviewed journals and poster presentations.

BIO-CAT holds numerous patents including more than a dozen awarded to our founder, Ed Schuler. A noteworthy example, we were awarded a patent in 2005 for the extraction and use of a hyaluronidase enzyme to aid in ophthalmic treatments.

Woman wearing safety glasses working in a laboratory